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ODN 1585 (sodium) is a potent inducer of IFN and TNFα production, and a strong stimulator of NK (natural killer) cell function. It increases CD8+ T-cell function, including IFN-γ production. This product has been shown to induce regression of established melanomas and offer complete protection against malaria in mice. It can be used for acute myelogenous leukemia (AML) and malaria research, and also serves as a vaccine adjuvant.
Potent inducer of IFN and TNFα production
Strong stimulator of natural killer (NK) cell function
Increases CD8+ T-cell function and IFN-γ production
Induces regression of established melanomas
Confers protection against malaria
Applicable for acute myelogenous leukemia (AML) and malaria research
Functions as a vaccine adjuvant
Induces PBMC to produce IFN-α
Stimulates NK cell-mediated lysis of K562 cells
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